Tom Metz

Metabolomics in Health & Disease II

Abstract Title: Aiding diagnosis of rare disease: applications of mass spectrometry-based metabolomics in the Undiagnosed Diseases Network

Thursday 13:45 - 14:15

Tom Metz received his Ph.D. in Chemistry from the University of South Carolina, using mass spectrometry to study the role of the Maillard reaction in the development of diabetic complications and in aging. He then conducted post-doctoral studies in separations coupled with mass spectrometry at Pacific Northwest National Laboratory (PNNL) with a major focus on metabolomics and minor focus on proteomics.

Currently, he is a staff scientist and the metabolomics technical lead in the Integrative Omics group at PNNL, as well as the Team Lead for a group of scientists that focuses on applications of high throughput proteomics, metabolomics, and lipidomics methods to various biological questions. His research has focused on the development of both untargeted and targeted metabolomics and lipidomics capabilities based on chromatographic and other separations coupled with mass spectrometry, for fundamental studies of metabolism and metabolic interactions, as well as for biomarker discovery in the context of both chronic and infectious disease.